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How to Put Your Dog to Sleep Using Benadryl If circumstances need you to be away from your pet during euthanasia, know that your vet will work quickly, quietly, and painlessly. First, you"ll need to take care of a few things: how to euthanize a rabbit at home with benadryl The veterinarian will give a thorough demonstration of the procedure before beginning. Please ask any questions that may come to mind to ensure your understanding. Have your dog lay down calmly, and then phone for help. Inconveniencing the vet or his staff at this time is strongly discouraged. Before administering Benadryl, an intravenous catheter (IV) can be placed into a vein to reduce the risk of a painful rupture. The veterinarian will give your dog a lethal amount of Benadryl, putting him or her into a deep sleep that will last for a few minutes at the very least. The vet will listen to the dog"s heart with a stethoscope to confirm that he or she has passed away. A response, such as cram